Tissue plasminogen activator for acute ischemic stroke: Is the CAEP Position Statement too negative?

Abstract

It is clear that no consensus exists regarding the appropriateness of tPA for acute ischemic stroke. The CAEP committee's willingness to acknowledge this, to recognize the limitations of the therapy, and to recommend appropriate caution, is a tremendously positive step. It should be applauded heartily by all of us who do our best to make difficult decisions, under enormous time stresses – regardless of whether we suspect that tPA will ultimately prove, on balance, and in community practice, to do more good, or more harm, in patients with suspected stroke. © 2001, Canadian Association of Emergency Physicians. All rights reserved.