Journal ArticleOPEN ACCESS

Differentiated Care Pathways for Antiretroviral Therapy Monitoring in Malawi: Expanding Viral Load Testing in Setting of Highly Prevalent Resistance

  • Rutstein S
  • Compliment K
  • Nelson J
  • et al.
Open Forum Infectious Diseases (2017) 4(3)
DOI: 10.1093/ofid/ofx125
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Abstract

We quantified resistance to first-line antiretroviral therapy among previously unmonitored patients in Malawi with viremia (≥1000 copies/mL). Ninety-five percent (n = 57/61) harbored nucleoside/tide reverse transcriptase inhibitor/non-nucleoside reverse transcriptase inhibitor resistance; resistance was more common comparing >2 (97%) versus ≤2 years (87%) on therapy. Immediate switch for persons retained in care may improve monitoring efficiency and maximize clinical outcomes.

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Rutstein, S. E., Compliment, K., Nelson, J. A. E., Kamwendo, D., Mataya, R., Miller, W. C., & Hosseinipour, M. C. (2017). Differentiated Care Pathways for Antiretroviral Therapy Monitoring in Malawi: Expanding Viral Load Testing in Setting of Highly Prevalent Resistance. Open Forum Infectious Diseases, 4(3). https://doi.org/10.1093/ofid/ofx125

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