Yeast Polo-like kinase substrates are nailed with the right tools.

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Abstract

A platform has been built combining chemical genetics and bioinformatics to screen the proteome for physiological substrates of the Polo-like kinase in budding yeast. A novel role for this kinase in regulating the mitotic spindle is revealed.

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Archambault, V., & Glover, D. M. (2008). Yeast Polo-like kinase substrates are nailed with the right tools. Genome Biology. https://doi.org/10.1186/gb-2008-9-1-203

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