Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is defined by minimum inhibitory concentrations of methicillin of 16 µg/mL or more or oxacillin 4 µg/mL or more (1). Strains of MRSA possess the mecA gene (1,2). This chromosomal gene encodes an altered enzyme, termed penicillin-binding protein 2a (or PBP20), which has a low affinity for all beta-lactam antibiotics. As a rule, strains of MRSA also possess resistance determinants for many other antimicrobial agents.
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CITATION STYLE
Yoshikawa, T. T., & Strausbaugh, L. J. (2006). Methicillin-resistant staphylococcus aureus. In Infection Management for Geriatrics in Long-Term Care Facilities, Second Edition (pp. 391–409). CRC Press. https://doi.org/10.12968/jowc.1998.7.sup2.21
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