Skin Barrier Changes in T1DM and T2DM

Abstract

Cutaneous manifestations of diabetes mellitus (DM) are a group of skin disorders that characteristically arise from prolonged chronic hyperglycemia and impaired insulin signaling or insulin resistance. There are several skin diabetic pathologies associated with the two main types of diabetes-type 1 (T1DM) and type 2 diabetes (T2DM), which tend to negatively impact the patients quality of life.