Progressive supranuclear palsy

19Citations
Citations of this article
11Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia. PSP is defined neuropathologically by the accumulation of neurofibrillary tangles in the subthalamic nucleus, pallidum, red nucleus, substantia nigra, striatum, pontine tegmentum, oculomotor nucleus, medulla and dentate nucleus. Over the last decade many lines of investigations have helped refine PSP in many aspects and it is the purpose of this review to help neurologists identify PSP, to better understand its pathophysiology and to provide a more focused, symptom-based treatment approach.

Cite

CITATION STYLE

APA

Barsottini, O. G. P., Felício, A. C., de Aquino, C. C. H., & Pedroso, J. L. (2010). Progressive supranuclear palsy. Arquivos de Neuro-Psiquiatria. Associacao Arquivos de Neuro-Psiquiatria. https://doi.org/10.1590/S0004-282X2010000600020

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free