Experimental evidence suggested the existence of unidentified leprosy susceptibility loci in the human leukocyte antigen (HLA) complex. To identify such genetic risk factors, a high-density association scan of a 1.9-mega-base (Mb) region in the HLA complex was performed. Among 682 single-nucleotide polymorphisms (SNPs), 59 were associated with leprosy (P
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Alter, A., Huong, N. T., Singh, M., Orlova, M., Van Thuc, N., Katoch, K., … Schurr, E. (2011). Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India. Journal of Infectious Diseases, 203(9), 1274–1281. https://doi.org/10.1093/infdis/jir024