Effects of yohimbine on novel open field exploration of mice

Abstract

The effects of the anxiogenic compound yohimbine on exploration of a novel open field was investigated. The drug had no effect on latency to enter the open field but produced a marginally significant increase in number of open field entries. The results suggest that yohimbine may have behavioral stimulant and/or anticonflict properties under some testing conditions. Such effects may limit its usefulness as a research tool for the study of anxiety. © 1990, The Psychonomic Soceity, Inc.. All rights reserved.