South Korea's COVID-19 Infection Status: From the Perspective of Re-positive Test Results after Viral Clearance Evidenced by Negative Test Results

Abstract

Coronavirus disease (COVID-19) started to occur in South Korea by means of inflow of the virusfrom abroad, when a case from Wuhan, China, was first confirmed on January 19, 2020. Although SouthKorea has drastically reduced the number of new confirmed cases and is stabilizing the situation with its exemplary disease prevention policies, there remains a problem. These are cases that had shown negative results to polymerase chain reaction (PCR) (gene amplification) tests as the COVID-19 virus had become undetectable but turned re-positive after a short period. The Central Clinical Committee determined that these re-positive cases after COVID-19 viral clearance are due to the limits of the test method; it is considered that the genetic material of the dead virus remaining in a recovered patient's body is amplified during the test process. Comprehending the above evidence, re-positive cases of COVID-19 are not infectious; the virus is not even reactivated. However, further research is required as we lack research results on this subject. Until we can be sure, social distancing and other such policies should be maintained.