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LRP1B functions as a receptor for Pseudomonas exotoxin

Biochimica et Biophysica Acta - Molecular Basis of Disease (2005) 1741(3) 234-239
DOI: 10.1016/j.bbadis.2005.06.007
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Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors, among them Pseudomonas Exotoxin A (PE). Previously, low-density lipoprotein receptor-related protein 1 (LRP1) was shown to be the primary receptor for PE. In this report, we show that a close family member, LRP1B, can also function as a receptor.

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Pastrana, D. V., Hanson, A. J., Knisely, J., Bu, G., & FitzGerald, D. J. (2005). LRP1B functions as a receptor for Pseudomonas exotoxin. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1741(3), 234–239. https://doi.org/10.1016/j.bbadis.2005.06.007

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