A Nobel Prize for membrane traffic: Vesicles find their journey's end

Abstract

Cell biologists everywhere rejoiced when this year's Nobel Prize in Physiology or Medicine was awarded to James Rothman, Randy Schekman, and Thomas Südhof for their contributions to uncovering the mechanisms governing vesicular transport. In this article, we highlight their achievements and also pay tribute to the pioneering scientists before them who set the stage for their remarkable discoveries. © 2013 Mellman and Emr.