Atropine toxicity in a neonate

Abstract

Summary: This case report is of a child who suffered a toxic reaction to an overdose of atropinc and then of physostigmine. The central anti-cholinergic toxicity of the atropine was initially reversed by physostigmine resulting in an incipient muscarinic crisis. This crisis was averted by glycopyrrolate, thereby allowing completion of the reversal with physostigmine. © 1974 John Sherratt and Son Ltd.