Use of BMDS and PROAST software packages by EFSA Scientific Panels and Units for applying the Benchmark Dose (BMD) approach in risk assessment

Abstract

Suggested citation: European Food Safety Authority; 2011. Use of BMDS and PROAST software packages by EFSA Scientific Panels and Units for applying the Benchmark Dose (BMD) approach in risk assessment. EN-113. [190 pp.]. Slob for the preparation of the workshop, and EFSA staff: Bernard Bottex and Olaf Mosbach-Schulz for the support provided to this scientific output. Use of BMDS and PROAST to derive a Benchmark Dose 2 EN-113 SUMMARY In May 2009, the EFSA Scientific Committee (SC) adopted its guidance on the use of the benchmark dose (BMD) approach in risk assessment. The Scientific Committee concluded that the BMD approach is a scientifically more advanced method to the No-Observed-Adverse-Effect-Level (NOAEL) approach for deriving a Reference Point (RP), and therefore recommended EFSA Scientific Panels and Units to adopt the BMD approach for the risk assessment of chemicals in food. The Scientific Committee also suggested that training is organised for Panel experts and EFSA staff to build further expertise and facilitate the introduction of this approach in EFSA's risk assessments.