Analisis Model Stokastik Penularan Virus Hepatitis B

Abstract

The spread of hepatitis B virus (HBV) infection has been widely studied using the deterministic SIR model, in which individuals who recover from acute infection have temporary immunity to the virus. However, this deterministic model uses a constant rate of viral infection over time. This is not in accordance with the fact that the infection rate is a random parameter that depends on time. This study discusses the analysis of the stochastic model of hepatitis B virus transmission. The purpose of this study is to construct the SIR stochastic model by dividing the infection rate into two, namely the rate of acute and chronic infection following the Wiener process. The model is then searched for an analytical solution referring to the Ito formula. The analytical solution and the Wiener process are described by substituting parameter values in the form of acute and chronic infection rates (β+α), cure rate (γ), and initial values (S(0) and I(0)) to obtain the mean value (μ). and the standard deviation (σ) of dS(t) and dI(t). The results of the simulation show that the number of infected individuals (I(t)) will decrease rapidly if (γ) is greater but will increase rapidly if (β+α) and (I(0)) are greater.