Effectiveness of the active ingredients (Capixyl, Procapil, and rosemary extract) of the Trust? tonic for the treatment of androgenetic alopecia in comparison to minoxidil

Abstract

Background: Androgenic alopecia (AGA) is a common hair loss disorder seen in both males and females and continues by presenting thinning and miniaturization because of androgens, genetics, extracellular matrix (ECM) protein destruction, and micro-inflammation. The most common treatments for AGA used in males are minoxidil and finasteride. These drugs have an effective role in the recovery and retardation of hair loss; however, there are different side effects and limitations to their efficacy. Materials and Methods: In this research, we compared the effectiveness of the Trust tonic’s active complex, Capixyl, Procapil, and rosemary extract (CPR), and 2% minoxidil solution in reducing hair loss and stimulating hair growth. The study was conducted on two groups of male subjects with an average of 45 years for twenty-four weeks using 1 ml of each solution everyday in the morning and evening.