Avaliação da atividade cicatrizante de preparados à base de jucá (Caesalpinia ferrea Mart.)

Abstract

The Caesalpinia ferrea, popularly known as jucá, has many proven pharmacological activities. In northeastern Brazil this plant is often used to treat skin wounds, with good results, which arouses great interest in the biotech and pharmacological studies of this kind. The aim of this study was to evaluate the healing activity of jucá pod (C. ferrea) alone or in combination with sugar, healing of skin wounds in rabbits. 40 rabbits were used (Oryctalagus cunicullus) adults, divided into five groups: control, the pods powder fresh, pod powder in natura added sugar (1: 1), jucá ointment with glycerin vehicle, and jucá plus sugar glycerin ointment vehicle, administered three times a day. After anesthesia was dissociative manufacture of surgical wounds standardized in size 2,5 cm2. Daily clinical, macroscopic and histological analyzes of lesions in three ten days after the surgical preparation of the wounds were made. The results showed no significant difference between the groups regarding the healing time, but topical treatment with ointment formulated with the powder coming from jucá pod caused a significant increase in the lesion area of the contraction in the third and tenth day.