Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil

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Abstract

The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance.

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Contreras Mejía, M. D. C., Dos Santos, M. P., Da Silva, G. A. V., Da Motta Passos, I., Naveca, F. G., Cunha, M. D. G. S., … De Paula, L. (2014). Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil. Journal of Clinical Microbiology, 52(12), 4359–4360. https://doi.org/10.1128/JCM.01688-14

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