Fluorescent Nanomaterials for Detection and Discrimination of Amino Acids

Abstract

The incessant surge and urge for amino acids (AAs) detection and discrimination has led scientists devoting extensive research efforts toward realizing an efficiently more robust methods/techniques for AAs recognition using different materials considering their crucial health impacts in the body system metabolism. Notably, fluorescent probes (FPs), as obviously known currently, are powerful noninvasive detection tools which are suitable and highly effective for biomolecules recognition displaying high-resolution images. The last decade has witnessed exciting achievements in AAs sensing via the use of FPs and integrated probes with colorimetric sensors reviewed in 2012. However, the conducted study discovers that more advance and effective sensing along with innovative segregation methods for AAs are yet to be vastly unveiled owing to discrimination difficulties among various AAs. As a result, herein, the strategic study accounts for some recent progressive achievements made from 2013 to date for AAs recognition and discrimination via the use of fluorescent nanomaterials (FNMs) of nanoparticles, nanoclusters, and nanodots along with quantum dots (QDs) in different ways. The study concludes by outlining the sensitivity and selectivity extent of AAs, the FNMs, and QDs supramolecular chemistry studies for cancer cells, and finally their status quo based on the views and assumed perspectives.