Resistance training effect on serum insulin-like growth factor 1 in the serum: a meta-analysis

Abstract

Background: The resistance exercise has drawn considerable attention to the level of insulin-like growth factor 1 in the serum. However, the relationship between resistance exercise and the level of insulin-like growth factor 1 in the serum is conflicting. This meta-analysis was performed to evaluate this relationship. Methods: A systematic literature search up to May 2020 was performed and 22 studies were detected with 680 subjects. They reported relationships between resistance exercise and the level of insulin-like growth factor 1 in the serum. Odds ratio (OR) with 95% confidence intervals (CIs) was calculated comparing the resistance exercise and the level of insulin-like growth factor 1 in the serum using the continuous method with a random or fixed-effect model. Results: Significantly higher insulin-like growth factor 1 was observed in subjects performing resistance training for less than 16 weeks (OR, 4.03; 95% CI, 2.49–5.57, p