Simultaneous presence of two hematological malignancies: Chronic lymphocytic leukemia and myelofibrosis in a patient

Abstract

Coexistence of chronic lymphocytic leukemia (CLL) with myelofibrosis is a rare association with only isolated case reports in the literature. We report an unusual case of CLL in which the cause of anemia was coexistent myelofibrosis. In a case of CLL presenting with refractory anemia, besides common causes like autoimmune hemolytic anemia and marrow infiltration, other causes like myelofibrosis should be searched for. © 2010 Indian Society of Haematology & Transfusion Medicine.