Ionic Liquid Based Vilsmeier Reagent as a Substitute for Mitsunobu Reagent: Direct Conversion of Alcohols into Different Compounds under Ionic Liquid Conditions

Abstract

The ionic liquid based methylchloroiminium chloride reagent (Vilsmeier reagent) derived from DMF-like multipurpose functional ionic liquid has been used as an efficient and reusable reagent for Mitsunobu reaction. Variety of different alcohols has been converted into different classes of compounds under ionic liquid conditions. The present system offers a competitive and better alternative to routine Mitsunobu protocol.