Monkeypox: A Growing Concern for Pulmonary Health

Abstract

The re-emergence of monkeypox as a significant global health concern has highlighted the need to reassess its clinical presentation, particularly its impact on pulmonary health. Traditionally associated with dermatological symptoms, recent outbreaks in non-endemic regions have underscored the virus's potential for widespread transmission and respiratory complications. Emerging evidence indicates that monkeypox infection can lead to respiratory symptoms such as cough, sore throat, and, in severe cases, pneumonia and acute respiratory distress syndrome (ARDS). The virus's capacity for respiratory transmission, coupled with the potential for coinfection with other respiratory pathogens, poses significant challenges for clinical management. Understanding the pathophysiology of monkeypox's impact on the lungs, which may involve direct viral invasion and immune-mediated damage, is critical for developing effective public health strategies. As monkeypox continues to spread, recognizing and addressing its respiratory complications will be essential in mitigating severe outcomes, particularly in vulnerable populations with pre-existing pulmonary conditions.; Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Georgakopoulou et al.)