Cancer cells use exosomes as tools to manipulate immunity and the microenvironment

Abstract

Exosomes are small vesicles secreted in relative abundance by cancer cells, which may prove useful as disease markers. However, exosomes also exhibit potent functions; modulating the behavior of immune- and other cells. Bridging our understanding of their molecular phenotype and functional mechanisms will provide key insight into their importance in cancer. © 2012 Landes Bioscience.