Characterization of pharmacological properties of methanolic seed and stem bark extracts of Ziziphus mauritiana (BAU Kul) using in-vitro and in-vivo animal (Swiss albino male mice) model

Abstract

Background: Ziziphus mauritiana belongs to family of Rhamnaceae, is an improved fast-growing variety of plum and seasonal fruit which is very popular and commonly known as "BAU Kul" in Bangladesh. This study was designed to evaluate the medicinal values of seed and stem bark extracts of Ziziphus mauritiana. Methods: Antioxidant, thrombolytic, membrane stabilizing, cytotoxic and antimicrobial activities were characterized using in-vitro methods and anti-diarrheal, analgesic and hypoglycemic activities were evaluated in Swiss albino male mice. The coarse powder of the plant parts were extracted with methanol and methanol portion of the extract was evaporated naturally under room temperature. Then the dried plant extracts were undergone for subsequent investigation.