Acute phase proteins, C9, factor B, and lysozyme in recurrent oral ulceration and Behcet's syndrome

Abstract

The concentrations and sequential changes of some acute phase proteins, factor B, and lysozyme have been assayed in recurrent oral ulceration and Behcet's syndrome. C9 was elevated in both groups of patients and was the most sensitive index of disease activity; however, it failed to discriminate between the 3 types of recurrent oral ulcers and 4 types of Behcet's syndrome. The level of αl acid glycoprotein and lysozyme were significantly increased predominantly in the ocular type, whereas factor B was significantly increased especially in the neurological type of Behcet's syndrome. It is suggested that the changes in the concentrations of some plasma proteins may help understanding of tissue involvement in Behcet's syndrome, as well as in the selection of therapeutic agents in this disease.