Changing Trends in the Cysticercosis–Related Disease Burden from 1990 to 2021 and its Predicted Level in 2022–2050 Years

Abstract

Background: A major worldwide health concern is cysticercosis, a zoonotic parasitic illness brought on by human parasites. This study aims to examine the current worldwide cysticercosis burden in order to serve as a resource for developing successful global control initiatives. Methods: Five layers of data about cysticercosis were analyzed: gender, age, year, and the regional and national social and economic development index (SDI). The various groups were compared using age-standardized rates, and patterns in the burden of disease were examined and evaluated. Furthermore, from 2022 to 2050, disease patterns were predicted using the ARIMA and ES models. Results: It was discovered that compared with 1990, the number of deaths decreased by 362 in 2021, the prevalence number increased by 1,318,963, the DALYs decreased by 151,192, and the age-standardized Mortality rate (ASMR) decreased by 0.02 per 100,000 people (EAPC − 2.39, 95% CI − 2.46 to − 2.32), the age-standardized DALY rate (ASDR) decreased by 9.14 per 100,000 people (EAPC − 1.84, 95% CI − 1.93 to − 1.75), and the age-standardized prevalence rate (ASPR) decreased by 17.18 per 100,000 people (EAPC − 1.2, 95% CI − 1.3 to − 1.1). Conclusions: To sum up, although the prevalence of cysticercosis has dramatically declined globally over the last 30 years, it is still high in many low-SDI nations and regions. Therefore, in order to further optimize prevention and control methods and lower the burden of disease in high-burden regions and countries, it is imperative that international cooperation be strengthened.