Hand-foot-and-mouth Syndrome in Humans: Coxsackie A10 Infections in New Zealand

Abstract

Coxsackie A10 virus strains were isolated from four of nine patients with hand-foot-and-mouth disease. The patients showed no significant serum-neutralizing antibody titre. A survey on “ normal ” sera showed that 50% of the population develop antibodies to Coxsackie A10 virus by the time they reach 5 years of age. Various aspects of the epidemiology of, and immunological response to, the Coxsackie A10 virus are discussed, and compared with the properties of Coxsackie A5 and A16 virus strains, which also cause hand-foot-and-mouth disease syndrome. © 1968, British Medical Journal Publishing Group. All rights reserved.