A Novel Method for the Preparation of 3-Amino-4-Hydroxybenzenesulfonamide Precursors of “Acid Alizarin Violet N” Derivatives

Abstract

Chlorosulfonation of 2-nitroanisole gave 4-methoxy-3- nitrobenzenesulfonyl chloride (7) which was converted with N-butyl(3- phenylpropyl)amine into benzenesulfonamide (8). Hydrolysis of the ether and reduction of the nitro group of 8 followed by diazotization and coupling with 2- naphthol gave N-Butyl-N-(3-phenylpropyl)-4-hydroxy-3-(2-hydroxy- l-naphthyl)azobenzenesulfonamide (1d). © 1993, Taylor & Francis Group, LLC. All rights reserved.