Candida spp. with acquired echinocandin resistance, France, 2004-2010

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Abstract

We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.

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Dannaoui, E., Desnos-Ollivier, M., Garcia-Hermoso, D., Grenouillet, F., Cassaing, S., Baixench, M. T., … Lortholary, O. (2012). Candida spp. with acquired echinocandin resistance, France, 2004-2010. Emerging Infectious Diseases, 18(1), 86–90. https://doi.org/10.3201/eid1801.110556

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