Abstract
A series of cinchona alkaloid-derived dimeric quaternary ammonium salts were prepared as chiral phase-transfer catalysts by the introduction of various functional groups on the phenyl ligand. Among them, the 2-F-substituted derivative 21 showed the highest enantioselectivity in the alkylation of the glycine anion equivalent 1 (97 to >99% ee). © 2003 Elsevier Science Ltd. All rights reserved.
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CITATION STYLE
APA
Park, H. G., Jeong, B. S., Yoo, M. S., Lee, J. H., Park, B. S., Kim, M. G., & Jew, S. S. (2003). Highly efficient ortho-fluoro-dimeric cinchona-derived phase-transfer catalysts. Tetrahedron Letters, 44(17), 3497–3500. https://doi.org/10.1016/S0040-4039(03)00687-7
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