Structure and Biological Activity of Furocoumarins

Abstract

In this review we summarize the structure and biological effects of linear and angular psoralens. These compounds exhibit very interesting biological effects on cell cycle, apoptosis and differentiation. These molecules should be considered as promising drugs in the therapy of several diseases, including psoriasis, mycosis fungoides, cancer. In addition, pre-clinical data demonstrate a possible employment of these molecules for the treatment of β-thalassemia.