Abstract
Several thiazolone-based sulfonamides were prepared, utilizing various hetero-aryl sulfonyl chlorides and different aldehydes, as inhibitors of NS5B polymerase, to target HCV. The best compound showed 0.6 nM of IC50 inhibitory activity. © 2006 Elsevier Ltd. All rights reserved.
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APA
Ding, Y., Smith, K. L., Varaprasad, C. V. N. S., Chang, E., Alexander, J., & Yao, N. (2007). Synthesis of thiazolone-based sulfonamides as inhibitors of HCV NS5B polymerase. Bioorganic and Medicinal Chemistry Letters, 17(3), 841–845. https://doi.org/10.1016/j.bmcl.2006.08.104
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