Studies on the chemical constituents of antifertility plant gardenia jasminoides ellis I: The structure of gardenoic acid B, and early pregnancy terminating component

  • Rensheng X
  • Guowei Q
  • Dayuan Z
  • et al.
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Abstract

The flowers of G. jasminoides are used in Chinese folk medicine for birth control. EtOAc extract of the flowers showed significant effects on terminating early pregnancy in rats. Flash column chromatog. separation of the crude extract gave several components among which 2 new cycloartane triterpenoids, namely gardenic acid and gardenolic acid B (I) were active components. The structure of I, m.p. 214-216癈, [a]D17 + 51.2, C30H46O5, were deduced by spectral analyses on the acid and the diacetate II.

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Rensheng, X., Guowei, Q., Dayuan, Z., Zhiyun, F., Fuxiang, J., Boxi, Z., … Yulan, W. (1987). Studies on the chemical constituents of antifertility plant gardenia jasminoides ellis I: The structure of gardenoic acid B, and early pregnancy terminating component. Acta Chimica Sinica, 45(3), 301–304.

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