Alkaline reflux in Esophageal mucosa in rats. Histological study with and without N-amyl-N-methylnitrosamine

  • Yamamuro E
  • Polakiewicz B
  • Iriya K
  • et al.
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Abstract

The effect of duodenoesophageal reflux induced by total gastrectomy with and without low dose of N-amyl-N-methylnitrosamine (AMN) was studied in the rat esophagus. The results of this study suggest that reflux of duodenal contents may play an important role in the development of columnar epithelium. Tendency to dysplasia was observed in association low dose of AMN.

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Yamamuro, E., Polakiewicz, B., Iriya, K., Lopasso, F., Laudanna, A., Gama-Rodrigues, J., … Pinotti, H. (2001). Alkaline reflux in Esophageal mucosa in rats. Histological study with and without N-amyl-N-methylnitrosamine. Recent Advances in Diseases of the Esophagus, 45–46. Retrieved from <Go to ISI>://WOS:000174896000008

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