Pharmacological study on Panax ginseng C.A.Meyer.V.Effects of red ginseng on the experimental disseminated intravascular coagulation (4).On ginsenoside Rg3, Rh1 and Rh2

Abstract

20S, 20R ginsenoside Rg3, 20S, 20R ginsenoside Rh1, and ginsenoside Rh2 isolated from red ginseng were investigated for their effect on blood platelet aggregation and thrombin-induced conversion of fibrinogen to fibrin in vitro. 20S, 20R ginsenoside Rg3 inhibited collagen- and ADP-induced blood platelet aggregation. 20S ginsenoside Rg3, 20S, 20R ginsenoside Rh1 inhibited the thrombin-induced conversion of fibrinogen to fibrin.