Research Investigator I

Expiring today

Employer
Location
Cambridge, MA, US
Salary
Competitive
Posted
Nov 15, 2018
Closes
Dec 13, 2018
Ref
UZppBQARwWgQ
Discipline
Medicine, Medical
Contract Type
Full Time
Job Type
Other job types
We are seeking a scientist to join the Selection Technologies and Protein Engineering group at our new state-of-the-art facility in Cambridge, MA. You will be responsible for using library-based protein engineering techniques to solve drug discovery challenges across therapeutic areas, and evaluating and implementing new technologies.

Position Responsibilities:
  • Design and execute experiments to discover protein therapeutics by immunization and/or by in vitro selection using random libraries
  • Carry out a wide variety of molecular biology and protein-based techniques to achieve project goals
  • Analyze and interpret data to correlate protein sequence, structure and function
  • Contribute to protein engineering strategies for drug discovery around a therapeutic target or pathway
  • Collaborate in multi-disciplinary teams, communicate results both written and verbally with matrixed working groups


Qualifications:

Ph.D. in molecular biology, biotechnology, protein engineering or a related discipline with up to 5 years of additional relevant experience in academia or industry

Familiarity with library-based protein engineering methods such as phage display, mammalian display, yeast display or related methods is beneficial, and additional experience in any of the following areas would be desirable:
  • Single cell genomics using microfluidics or droplet-based methods for antibody discovery, fluorescent assays or in vitro selection
  • Analysis of display libraries or immune repertoires by next generation sequencing
  • Experience with analysis of protein structure
  • Experience working with complex or multi-specific biomolecules

Demonstrated ability to work and communicate with colleagues from different disciplines, and a history of successful collaborations. A proven track record of publication in peer-reviewed journals.